European Virtual Human Twin

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Mechanistic approaches|

Opinion/commentary|

Taxonomy|

Strobel, Gero, Frederik Möller, and Frederik Moeller. ‘HEALTHCARE IN THE ERA OF DIGITAL TWINS: TOWARDS A DOMAIN-SPECIFIC TAXONOMY’, 2022, 11.

TAG 1 2 27 3 37

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Mechanistic approaches|

Pharmaceutical (drug development etc.)|

Sokolov, Michael, Moritz von Stosch, Harini Narayanan, Fabian Feidl, and Alessandro Butté. ‘Hybrid Modeling — a Key Enabler towards Realizing Digital Twins in Biopharma?’ Current Opinion in Chemical Engineering 34 (December 2021): 100715.

TAG 1 15 2 3

Both Mechanistic and data-driven approaches|

Cell related|

Data-driven approaches|

Mechanistic approaches|

Review articles|

Tissue engineering|

Möller, Johannes, and Ralf Pörtner. ‘Digital Twins for Tissue Culture Techniques—Concepts, Expectations, and State of the Art’. Processes 9, no. 3 (2 March 2021): 447.

TAG 1 11 2 3 32 38

Both Mechanistic and data-driven approaches|

Cancer|

Data-driven approaches|

Mechanistic approaches|

Meraghni, Safa, Khaled Benaggoune, Zeina Al Masry, Labib Sadek Terrissa, Christine Devalland, and Noureddine Zerhouni. ‘Towards Digital Twins Driven Breast Cancer Detection’. In Intelligent Computing, edited by Kohei Arai, 285:87–99. Lecture Notes in Networks and Systems. Cham: Springer International Publishing, 2021.

TAG 1 2 3 9

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Mechanistic approaches|

Software|

Liu, Ying, Lin Zhang, Yuan Yang, Longfei Zhou, Lei Ren, Fei Wang, Rong Liu, Zhibo Pang, and M. Jamal Deen. ‘A Novel Cloud-Based Framework for the Elderly Healthcare Services Using Digital Twin’. IEEE Access 7 (2019): 49088–101.

TAG 1 2 3 33

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Mechanistic approaches|

Opinion/commentary|

Pandemic (virus related)|

Laubenbacher, Reinhard, James P. Sluka, and James A. Glazier. ‘Using Digital Twins in Viral Infection’. Science 371, no. 6534 (12 March 2021): 1105–6.

TAG 1 2 27 28 3

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Immune system|

Mechanistic approaches|

Opinion/commentary|

Laubenbacher, R., A. Niarakis, T. Helikar, G. An, B. Shapiro, R. S. Malik-Sheriff, T. J. Sego, A. Knapp, P. Macklin, and J. A. Glazier. ‘Building Digital Twins of the Human Immune System: Toward a Roadmap’. Npj Digital Medicine 5, no. 1 (December 2022): 64.

TAG 1 2 20 27 3

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Mechanistic approaches|

Opinion/commentary|

Pandemic (virus related)|

Review articles|

Khan, Asiya, Madison Milne-Ives, Edward Meinert, Gloria E Iyawa, Ray B Jones, and Alex N Josephraj. ‘A Scoping Review of Digital Twins in the Context of the Covid-19 Pandemic’. Biomedical Engineering and Computational Biology 13 (January 2022): 117959722211021.

TAG 1 2 27 28 3 32

Both Mechanistic and data-driven approaches|

Data-driven approaches|

Mechanistic approaches|

Stroke|

Herrgårdh, Tilda, Elizabeth Hunter, Kajsa Tunedal, Håkan Örman, Julia Amann, Francisco Abad Navarro, Catalina Martinez-Costa, John D. Kelleher, and Gunnar Cedersund. ‘Digital Twins and Hybrid Modelling for Simulation of Physiological Variables and Stroke Risk’. Preprint. Systems Biology, 27 March 2022.

TAG 1 2 3 35

Bone (orthopaedics)|

Both Mechanistic and data-driven approaches|

Cell related|

Data-driven approaches|

Mechanistic approaches|

Opinion/commentary|

Software|

Hernigou, Philippe, and Marius M. Scarlat. ‘Ankle and Foot Surgery: From Arthrodesis to Arthroplasty, Three Dimensional Printing, Sensors, Artificial Intelligence, Machine Learning Technology, Digital Twins, and Cell Therapy’. International Orthopaedics 45, no. 9 (September 2021): 2173–76.

TAG 1 11 2 27 3 33 7